Physical Properties | | | |
Molecular Weight: 374.505 g/mol | logS: -4.70131 | SlogP: 3.8494 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0964926 | Sterimol/B1: 2.47474 | Sterimol/B2: 4.13163 | Sterimol/B3: 4.92149 |
Sterimol/B4: 7.11748 | Sterimol/L: 17.2116 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 644.454 | Positive charged surface: 395.867 | Negative charged surface: 248.588 | Volume: 367.25 |
Hydrophobic surface: 499.181 | Hydrophilic surface: 145.273 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |