Physical Properties | | | |
Molecular Weight: 409.486 g/mol | logS: -2.54487 | SlogP: 0.60247 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.176722 | Sterimol/B1: 3.44722 | Sterimol/B2: 3.62795 | Sterimol/B3: 5.94162 |
Sterimol/B4: 6.70492 | Sterimol/L: 14.6826 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 597.784 | Positive charged surface: 405.297 | Negative charged surface: 192.487 | Volume: 362.5 |
Hydrophobic surface: 443.651 | Hydrophilic surface: 154.133 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |