Physical Properties | | | |
Molecular Weight: 304.286 g/mol | logS: -1.482 | SlogP: 2.99562 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.181611 | Sterimol/B1: 2.14927 | Sterimol/B2: 2.93718 | Sterimol/B3: 5.89328 |
Sterimol/B4: 8.352 | Sterimol/L: 14.301 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 532.158 | Positive charged surface: 363.657 | Negative charged surface: 168.501 | Volume: 280 |
Hydrophobic surface: 405.059 | Hydrophilic surface: 127.099 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |