Physical Properties | | | |
Molecular Weight: 393.511 g/mol | logS: -5.1658 | SlogP: 3.6147 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0902907 | Sterimol/B1: 2.37799 | Sterimol/B2: 2.52098 | Sterimol/B3: 5.88524 |
Sterimol/B4: 11.2792 | Sterimol/L: 18.5861 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 705.895 | Positive charged surface: 461.877 | Negative charged surface: 244.018 | Volume: 398.375 |
Hydrophobic surface: 567.878 | Hydrophilic surface: 138.017 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |