Physical Properties | | | |
Molecular Weight: 410.378 g/mol | logS: -4.12124 | SlogP: 1.93907 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.192287 | Sterimol/B1: 2.51292 | Sterimol/B2: 2.76645 | Sterimol/B3: 6.9262 |
Sterimol/B4: 7.92778 | Sterimol/L: 15.6285 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 608.933 | Positive charged surface: 408.521 | Negative charged surface: 200.412 | Volume: 353.625 |
Hydrophobic surface: 389.706 | Hydrophilic surface: 219.227 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |