Physical Properties | | | |
Molecular Weight: 343.386 g/mol | logS: -5.73881 | SlogP: 3.49987 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.260814 | Sterimol/B1: 2.55917 | Sterimol/B2: 4.23764 | Sterimol/B3: 6.42027 |
Sterimol/B4: 9.50385 | Sterimol/L: 13.3261 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 554.952 | Positive charged surface: 332.286 | Negative charged surface: 205.555 | Volume: 319.875 |
Hydrophobic surface: 413.466 | Hydrophilic surface: 141.486 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |