Physical Properties | | | |
Molecular Weight: 371.827 g/mol | logS: -7.45293 | SlogP: 5.8795 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.115041 | Sterimol/B1: 2.88374 | Sterimol/B2: 4.24033 | Sterimol/B3: 4.67664 |
Sterimol/B4: 5.74415 | Sterimol/L: 15.7706 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 555.161 | Positive charged surface: 296.304 | Negative charged surface: 258.856 | Volume: 337.5 |
Hydrophobic surface: 496.732 | Hydrophilic surface: 58.429 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |