Physical Properties | | | |
Molecular Weight: 420.502 g/mol | logS: -3.03638 | SlogP: 2.531 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0464294 | Sterimol/B1: 3.79387 | Sterimol/B2: 4.18618 | Sterimol/B3: 4.3054 |
Sterimol/B4: 6.5741 | Sterimol/L: 21.4711 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 755.144 | Positive charged surface: 523.602 | Negative charged surface: 231.542 | Volume: 417.75 |
Hydrophobic surface: 581.853 | Hydrophilic surface: 173.291 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |