Physical Properties | | | |
Molecular Weight: 404.49 g/mol | logS: -8.36585 | SlogP: 5.1152 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0657634 | Sterimol/B1: 2.21584 | Sterimol/B2: 5.76998 | Sterimol/B3: 5.92093 |
Sterimol/B4: 7.3171 | Sterimol/L: 19.5256 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 697.781 | Positive charged surface: 526.726 | Negative charged surface: 166.23 | Volume: 399.375 |
Hydrophobic surface: 553.537 | Hydrophilic surface: 144.244 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |