Physical Properties | | | |
Molecular Weight: 408.362 g/mol | logS: -5.68595 | SlogP: 2.78657 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0226869 | Sterimol/B1: 2.4335 | Sterimol/B2: 3.73082 | Sterimol/B3: 4.80738 |
Sterimol/B4: 5.91965 | Sterimol/L: 16.9863 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 601.557 | Positive charged surface: 383.731 | Negative charged surface: 207.445 | Volume: 348.625 |
Hydrophobic surface: 371.71 | Hydrophilic surface: 229.847 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |