Physical Properties | | | |
Molecular Weight: 425.593 g/mol | logS: -6.91617 | SlogP: 5.83932 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.287077 | Sterimol/B1: 2.47315 | Sterimol/B2: 4.05101 | Sterimol/B3: 7.22705 |
Sterimol/B4: 8.30416 | Sterimol/L: 14.1913 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 665.598 | Positive charged surface: 379.539 | Negative charged surface: 286.059 | Volume: 419.5 |
Hydrophobic surface: 523.396 | Hydrophilic surface: 142.202 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |