Physical Properties | | | |
Molecular Weight: 386.356 g/mol | logS: -4.05974 | SlogP: 2.34632 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.181643 | Sterimol/B1: 2.88368 | Sterimol/B2: 3.69888 | Sterimol/B3: 5.22418 |
Sterimol/B4: 8.25631 | Sterimol/L: 14.1618 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 586.61 | Positive charged surface: 324.323 | Negative charged surface: 262.288 | Volume: 338.125 |
Hydrophobic surface: 393.09 | Hydrophilic surface: 193.52 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |