Physical Properties | | | |
Molecular Weight: 383.472 g/mol | logS: -5.06798 | SlogP: 2.8804 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0779122 | Sterimol/B1: 2.80571 | Sterimol/B2: 3.53763 | Sterimol/B3: 4.35882 |
Sterimol/B4: 6.45244 | Sterimol/L: 17.9488 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 628.67 | Positive charged surface: 371.481 | Negative charged surface: 257.188 | Volume: 352.875 |
Hydrophobic surface: 463.658 | Hydrophilic surface: 165.012 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |