Physical Properties | | | |
Molecular Weight: 327.449 g/mol | logS: -4.77121 | SlogP: 3.0585 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.162425 | Sterimol/B1: 2.32582 | Sterimol/B2: 3.94691 | Sterimol/B3: 5.56599 |
Sterimol/B4: 6.27675 | Sterimol/L: 13.3059 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 499.801 | Positive charged surface: 224.387 | Negative charged surface: 275.413 | Volume: 272.875 |
Hydrophobic surface: 286.904 | Hydrophilic surface: 212.897 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |