Physical Properties | | | |
Molecular Weight: 351.422 g/mol | logS: -4.68231 | SlogP: 2.8932 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.133528 | Sterimol/B1: 2.33854 | Sterimol/B2: 4.27675 | Sterimol/B3: 4.34491 |
Sterimol/B4: 8.61372 | Sterimol/L: 16.424 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 609.157 | Positive charged surface: 363.033 | Negative charged surface: 246.124 | Volume: 352 |
Hydrophobic surface: 511.017 | Hydrophilic surface: 98.14 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |