Physical Properties | | | |
Molecular Weight: 304.353 g/mol | logS: -4.48062 | SlogP: 3.382 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00836152 | Sterimol/B1: 2.17136 | Sterimol/B2: 2.33287 | Sterimol/B3: 3.16527 |
Sterimol/B4: 5.49204 | Sterimol/L: 20.664 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 572.276 | Positive charged surface: 345.722 | Negative charged surface: 226.554 | Volume: 297.25 |
Hydrophobic surface: 443.704 | Hydrophilic surface: 128.572 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |