Physical Properties | | | |
Molecular Weight: 391.499 g/mol | logS: -5.0694 | SlogP: 4.1544 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.131866 | Sterimol/B1: 2.36277 | Sterimol/B2: 3.25286 | Sterimol/B3: 5.49809 |
Sterimol/B4: 10.8968 | Sterimol/L: 16.4283 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 661.874 | Positive charged surface: 352.463 | Negative charged surface: 309.41 | Volume: 371.75 |
Hydrophobic surface: 544.383 | Hydrophilic surface: 117.491 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |