Physical Properties | | | |
Molecular Weight: 300.375 g/mol | logS: -1.77384 | SlogP: -0.23783 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0622005 | Sterimol/B1: 2.80624 | Sterimol/B2: 4.17063 | Sterimol/B3: 4.89412 |
Sterimol/B4: 5.42738 | Sterimol/L: 15.3378 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 542.387 | Positive charged surface: 362.549 | Negative charged surface: 179.838 | Volume: 277.125 |
Hydrophobic surface: 350.227 | Hydrophilic surface: 192.16 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |