Physical Properties | | | |
Molecular Weight: 398.439 g/mol | logS: -4.92796 | SlogP: 3.703 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.195933 | Sterimol/B1: 3.96454 | Sterimol/B2: 5.16712 | Sterimol/B3: 6.64223 |
Sterimol/B4: 7.27145 | Sterimol/L: 15.3132 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 635.989 | Positive charged surface: 354.638 | Negative charged surface: 281.351 | Volume: 352 |
Hydrophobic surface: 418.395 | Hydrophilic surface: 217.594 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |