Physical Properties | | | |
Molecular Weight: 414.442 g/mol | logS: -4.47909 | SlogP: 3.5329 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.137469 | Sterimol/B1: 2.17475 | Sterimol/B2: 3.97188 | Sterimol/B3: 5.35501 |
Sterimol/B4: 8.74057 | Sterimol/L: 16.0949 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 625.11 | Positive charged surface: 371.864 | Negative charged surface: 242.404 | Volume: 357.25 |
Hydrophobic surface: 419.484 | Hydrophilic surface: 205.626 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |