Physical Properties | | | |
Molecular Weight: 374.416 g/mol | logS: -3.10989 | SlogP: 1.7281 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.10655 | Sterimol/B1: 2.36554 | Sterimol/B2: 4.6719 | Sterimol/B3: 6.09083 |
Sterimol/B4: 7.0454 | Sterimol/L: 15.7961 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 602.305 | Positive charged surface: 414.908 | Negative charged surface: 187.398 | Volume: 342.375 |
Hydrophobic surface: 328.343 | Hydrophilic surface: 273.962 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |