Physical Properties | | | |
Molecular Weight: 409.534 g/mol | logS: -6.00783 | SlogP: 4.2579 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.077527 | Sterimol/B1: 2.75027 | Sterimol/B2: 4.95355 | Sterimol/B3: 6.6928 |
Sterimol/B4: 7.18954 | Sterimol/L: 16.8495 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 683.092 | Positive charged surface: 383.363 | Negative charged surface: 299.729 | Volume: 378.75 |
Hydrophobic surface: 497.395 | Hydrophilic surface: 185.697 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |