Physical Properties | | | |
Molecular Weight: 404.503 g/mol | logS: -4.87472 | SlogP: 5.1226 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0367189 | Sterimol/B1: 2.13415 | Sterimol/B2: 3.52526 | Sterimol/B3: 3.86973 |
Sterimol/B4: 8.83076 | Sterimol/L: 19.7818 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 720.148 | Positive charged surface: 540.87 | Negative charged surface: 179.278 | Volume: 397.375 |
Hydrophobic surface: 563.094 | Hydrophilic surface: 157.054 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |