Physical Properties | | | |
Molecular Weight: 420.509 g/mol | logS: -4.30649 | SlogP: 4.3397 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0456041 | Sterimol/B1: 2.71703 | Sterimol/B2: 3.05591 | Sterimol/B3: 4.23864 |
Sterimol/B4: 8.79674 | Sterimol/L: 20.6964 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 715.473 | Positive charged surface: 487.925 | Negative charged surface: 227.548 | Volume: 413 |
Hydrophobic surface: 598.468 | Hydrophilic surface: 117.005 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |