Physical Properties | | | |
Molecular Weight: 402.498 g/mol | logS: -5.25385 | SlogP: 4.48552 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.023523 | Sterimol/B1: 2.19114 | Sterimol/B2: 3.69 | Sterimol/B3: 3.73754 |
Sterimol/B4: 6.99053 | Sterimol/L: 24.3361 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 732.299 | Positive charged surface: 499.547 | Negative charged surface: 232.752 | Volume: 399.375 |
Hydrophobic surface: 659.589 | Hydrophilic surface: 72.71 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |