Physical Properties | | | |
Molecular Weight: 514.718 g/mol | logS: -8.76001 | SlogP: 7.41002 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0571558 | Sterimol/B1: 3.28567 | Sterimol/B2: 4.45575 | Sterimol/B3: 4.58194 |
Sterimol/B4: 12.093 | Sterimol/L: 19.1279 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 817.521 | Positive charged surface: 502.101 | Negative charged surface: 315.42 | Volume: 497.875 |
Hydrophobic surface: 651.642 | Hydrophilic surface: 165.879 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |