Physical Properties | | | |
Molecular Weight: 391.427 g/mol | logS: -5.5807 | SlogP: 3.886 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.108037 | Sterimol/B1: 2.91316 | Sterimol/B2: 5.33281 | Sterimol/B3: 5.43182 |
Sterimol/B4: 8.37083 | Sterimol/L: 18.1383 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 684.888 | Positive charged surface: 451.225 | Negative charged surface: 233.663 | Volume: 371.25 |
Hydrophobic surface: 507.04 | Hydrophilic surface: 177.848 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |