Physical Properties | | | |
Molecular Weight: 418.921 g/mol | logS: -5.62075 | SlogP: 4.67344 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0660687 | Sterimol/B1: 2.20343 | Sterimol/B2: 3.62312 | Sterimol/B3: 5.85526 |
Sterimol/B4: 9.5322 | Sterimol/L: 22.281 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 773.136 | Positive charged surface: 491.32 | Negative charged surface: 281.817 | Volume: 405 |
Hydrophobic surface: 651.454 | Hydrophilic surface: 121.682 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |