Physical Properties | | | |
Molecular Weight: 364.49 g/mol | logS: -2.79138 | SlogP: -0.2241 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0958197 | Sterimol/B1: 2.57282 | Sterimol/B2: 3.74503 | Sterimol/B3: 4.07081 |
Sterimol/B4: 6.64879 | Sterimol/L: 16.5219 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 596.048 | Positive charged surface: 436.513 | Negative charged surface: 159.535 | Volume: 350.25 |
Hydrophobic surface: 493.718 | Hydrophilic surface: 102.33 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |