Physical Properties | | | |
Molecular Weight: 347.414 g/mol | logS: -4.45448 | SlogP: 3.3251 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.659257 | Sterimol/B1: 2.48895 | Sterimol/B2: 4.55107 | Sterimol/B3: 6.28074 |
Sterimol/B4: 9.60427 | Sterimol/L: 12.3056 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 560.709 | Positive charged surface: 341.608 | Negative charged surface: 219.101 | Volume: 341.5 |
Hydrophobic surface: 448.685 | Hydrophilic surface: 112.024 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |