Physical Properties | | | |
Molecular Weight: 425.576 g/mol | logS: -5.66329 | SlogP: 5.73859 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0953283 | Sterimol/B1: 2.11569 | Sterimol/B2: 4.24487 | Sterimol/B3: 4.27802 |
Sterimol/B4: 12.4066 | Sterimol/L: 18.2988 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 752.97 | Positive charged surface: 473.451 | Negative charged surface: 279.52 | Volume: 444.25 |
Hydrophobic surface: 692.649 | Hydrophilic surface: 60.321 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |