Physical Properties | | | |
Molecular Weight: 400.383 g/mol | logS: -6.05716 | SlogP: 3.3758 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0860578 | Sterimol/B1: 3.13412 | Sterimol/B2: 3.69177 | Sterimol/B3: 4.88094 |
Sterimol/B4: 11.1558 | Sterimol/L: 16.9085 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 694.641 | Positive charged surface: 453.396 | Negative charged surface: 235.911 | Volume: 361.25 |
Hydrophobic surface: 479.111 | Hydrophilic surface: 215.53 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |