Physical Properties | | | |
Molecular Weight: 415.449 g/mol | logS: -6.49228 | SlogP: 4.9212 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.104176 | Sterimol/B1: 2.47531 | Sterimol/B2: 2.54566 | Sterimol/B3: 6.94665 |
Sterimol/B4: 10.8647 | Sterimol/L: 17.0487 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 707.269 | Positive charged surface: 489.686 | Negative charged surface: 200.769 | Volume: 387 |
Hydrophobic surface: 558.727 | Hydrophilic surface: 148.542 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |