Physical Properties | | | |
Molecular Weight: 403.87 g/mol | logS: -5.06992 | SlogP: 3.3762 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.044098 | Sterimol/B1: 2.37793 | Sterimol/B2: 3.72449 | Sterimol/B3: 4.34687 |
Sterimol/B4: 7.87444 | Sterimol/L: 19.0276 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.046 | Positive charged surface: 509.344 | Negative charged surface: 134.799 | Volume: 364.375 |
Hydrophobic surface: 449.689 | Hydrophilic surface: 199.357 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |