Physical Properties | | | |
Molecular Weight: 522.645 g/mol | logS: -8.37904 | SlogP: 6.62397 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.237764 | Sterimol/B1: 2.41229 | Sterimol/B2: 4.21488 | Sterimol/B3: 7.92275 |
Sterimol/B4: 9.22516 | Sterimol/L: 17.9075 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 779.352 | Positive charged surface: 484.908 | Negative charged surface: 289.594 | Volume: 515.75 |
Hydrophobic surface: 547.324 | Hydrophilic surface: 232.028 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |