Physical Properties | | | |
Molecular Weight: 404.26 g/mol | logS: -5.61919 | SlogP: 4.63177 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.195369 | Sterimol/B1: 2.27722 | Sterimol/B2: 3.79832 | Sterimol/B3: 6.45514 |
Sterimol/B4: 10.2354 | Sterimol/L: 15.836 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 625.486 | Positive charged surface: 360.836 | Negative charged surface: 261.268 | Volume: 339.375 |
Hydrophobic surface: 484.144 | Hydrophilic surface: 141.342 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |