Physical Properties | | | |
Molecular Weight: 401.527 g/mol | logS: -3.77156 | SlogP: 2.1742 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.292303 | Sterimol/B1: 2.91013 | Sterimol/B2: 6.60974 | Sterimol/B3: 6.65744 |
Sterimol/B4: 7.88178 | Sterimol/L: 15.5501 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 717.23 | Positive charged surface: 594.251 | Negative charged surface: 122.979 | Volume: 418.375 |
Hydrophobic surface: 616.691 | Hydrophilic surface: 100.539 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |