Physical Properties | | | |
Molecular Weight: 321.424 g/mol | logS: -6.0861 | SlogP: 5.0178 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0765845 | Sterimol/B1: 2.86423 | Sterimol/B2: 3.25652 | Sterimol/B3: 4.87464 |
Sterimol/B4: 8.23594 | Sterimol/L: 17.1185 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 619.977 | Positive charged surface: 398.838 | Negative charged surface: 221.139 | Volume: 331.875 |
Hydrophobic surface: 444.638 | Hydrophilic surface: 175.339 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |