Physical Properties | | | |
Molecular Weight: 385.491 g/mol | logS: -5.49256 | SlogP: 4.21805 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.185737 | Sterimol/B1: 2.74897 | Sterimol/B2: 4.84599 | Sterimol/B3: 7.06498 |
Sterimol/B4: 8.27609 | Sterimol/L: 18.8607 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 708.12 | Positive charged surface: 506.565 | Negative charged surface: 195.197 | Volume: 395.125 |
Hydrophobic surface: 482.533 | Hydrophilic surface: 225.587 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |