Physical Properties | | | |
Molecular Weight: 312.393 g/mol | logS: -3.48295 | SlogP: 3.32159 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.139848 | Sterimol/B1: 1.969 | Sterimol/B2: 4.09216 | Sterimol/B3: 5.99313 |
Sterimol/B4: 8.44238 | Sterimol/L: 13.3007 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 534.521 | Positive charged surface: 291.027 | Negative charged surface: 238.652 | Volume: 286.375 |
Hydrophobic surface: 414.121 | Hydrophilic surface: 120.4 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |