Physical Properties | | | |
Molecular Weight: 380.444 g/mol | logS: -4.18937 | SlogP: 3.36569 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.342562 | Sterimol/B1: 5.07372 | Sterimol/B2: 5.46878 | Sterimol/B3: 5.5305 |
Sterimol/B4: 5.83724 | Sterimol/L: 14.2 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.163 | Positive charged surface: 491.59 | Negative charged surface: 153.29 | Volume: 363.875 |
Hydrophobic surface: 594.471 | Hydrophilic surface: 54.692 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |