Physical Properties | | | |
Molecular Weight: 508.622 g/mol | logS: -7.4088 | SlogP: 6.1466 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.172046 | Sterimol/B1: 3.89453 | Sterimol/B2: 6.54466 | Sterimol/B3: 7.39292 |
Sterimol/B4: 8.80214 | Sterimol/L: 19.997 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 847.359 | Positive charged surface: 566.794 | Negative charged surface: 270.159 | Volume: 506.75 |
Hydrophobic surface: 690.513 | Hydrophilic surface: 156.846 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |