Physical Properties | | | |
Molecular Weight: 442.587 g/mol | logS: -5.57744 | SlogP: 5.4092 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.139068 | Sterimol/B1: 2.03669 | Sterimol/B2: 5.61426 | Sterimol/B3: 8.38795 |
Sterimol/B4: 8.48983 | Sterimol/L: 16.8024 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 722.271 | Positive charged surface: 445.441 | Negative charged surface: 271.71 | Volume: 430.25 |
Hydrophobic surface: 653.223 | Hydrophilic surface: 69.048 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |