Physical Properties | | | |
Molecular Weight: 403.39 g/mol | logS: -5.5822 | SlogP: 4.5272 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0470755 | Sterimol/B1: 3.24809 | Sterimol/B2: 3.3183 | Sterimol/B3: 4.44321 |
Sterimol/B4: 8.90149 | Sterimol/L: 20.3076 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 680.333 | Positive charged surface: 372.111 | Negative charged surface: 308.222 | Volume: 365.125 |
Hydrophobic surface: 467.43 | Hydrophilic surface: 212.903 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |