Physical Properties | | | |
Molecular Weight: 372.384 g/mol | logS: -7.31718 | SlogP: 4.90272 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0148324 | Sterimol/B1: 2.26811 | Sterimol/B2: 2.90942 | Sterimol/B3: 3.13481 |
Sterimol/B4: 9.11813 | Sterimol/L: 20.3658 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 651.529 | Positive charged surface: 342.841 | Negative charged surface: 308.688 | Volume: 342.25 |
Hydrophobic surface: 484.478 | Hydrophilic surface: 167.051 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |