Physical Properties | | | |
Molecular Weight: 395.551 g/mol | logS: -4.71643 | SlogP: 5.2285 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.105954 | Sterimol/B1: 2.24178 | Sterimol/B2: 2.39782 | Sterimol/B3: 5.58269 |
Sterimol/B4: 11.9739 | Sterimol/L: 18.048 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 710.222 | Positive charged surface: 513.512 | Negative charged surface: 196.71 | Volume: 411.5 |
Hydrophobic surface: 539.958 | Hydrophilic surface: 170.264 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |