Physical Properties | | | |
Molecular Weight: 391.539 g/mol | logS: -6.2028 | SlogP: 6.1378 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0947582 | Sterimol/B1: 2.23984 | Sterimol/B2: 3.99749 | Sterimol/B3: 6.2071 |
Sterimol/B4: 6.43706 | Sterimol/L: 18.2633 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 660.586 | Positive charged surface: 380.997 | Negative charged surface: 279.589 | Volume: 390.875 |
Hydrophobic surface: 561.064 | Hydrophilic surface: 99.522 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |