Physical Properties | | | |
Molecular Weight: 422.525 g/mol | logS: -5.06356 | SlogP: 4.45107 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0494265 | Sterimol/B1: 3.50727 | Sterimol/B2: 4.26487 | Sterimol/B3: 4.327 |
Sterimol/B4: 7.25463 | Sterimol/L: 19.9723 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 754.016 | Positive charged surface: 484.35 | Negative charged surface: 266.792 | Volume: 422.875 |
Hydrophobic surface: 542.49 | Hydrophilic surface: 211.526 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |