Physical Properties | | | |
Molecular Weight: 394.471 g/mol | logS: -4.03312 | SlogP: 3.81497 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0720935 | Sterimol/B1: 2.76798 | Sterimol/B2: 4.66774 | Sterimol/B3: 6.11971 |
Sterimol/B4: 7.42718 | Sterimol/L: 20.4305 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 716.28 | Positive charged surface: 456.181 | Negative charged surface: 257.275 | Volume: 387.75 |
Hydrophobic surface: 522.572 | Hydrophilic surface: 193.708 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |