Physical Properties | | | |
Molecular Weight: 416.271 g/mol | logS: -5.91545 | SlogP: 3.9578 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0641645 | Sterimol/B1: 3.5886 | Sterimol/B2: 3.66342 | Sterimol/B3: 4.3613 |
Sterimol/B4: 9.74688 | Sterimol/L: 16.6756 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 653.619 | Positive charged surface: 352.104 | Negative charged surface: 301.515 | Volume: 355.5 |
Hydrophobic surface: 538.007 | Hydrophilic surface: 115.612 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |